DunedinPACE
A third-generation epigenetic clock measuring the rate of biological aging, developed by Duke University researchers.
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The information provided on this page is for educational purposes only and does not constitute medical advice. Data suggests correlations, not diagnoses. Always consult a qualified healthcare professional before making health decisions based on biomarker data.
DunedinPACE (Pace of Aging Calculated from the Epigenome) was developed by Daniel Belsky, Avshalom Caspi, and Terrie Moffitt at Duke University and the University of Otago. Published in eLife (2022), it analyzes 173 CpG sites to determine how fast a person is aging. Unlike earlier clocks that estimate a static biological age, DunedinPACE captures the dynamic rate by training on longitudinal changes in 19 biomarkers measured at ages 26, 32, 38, and 45 in the Dunedin Study cohort (N=1,037). A score of 1.0 means aging at the population average rate; below 1.0 indicates slower aging; above 1.0 indicates faster aging. The typical population range is 0.6 to 1.4.— PaceSovereign Glossary
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References
- [1] Belsky DW, Caspi A, Corcoran DL, et al.. “DunedinPACE, a DNA methylation biomarker of the pace of aging.” eLife. 2022. doi:10.7554/eLife.73420